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Friederike Twele Selected Research

2,3- dioxo- 6- nitro- 7- sulfamoylbenzo(f)quinoxaline (NBQX)

1/2017A combination of NMDA and AMPA receptor antagonists retards granule cell dispersion and epileptogenesis in a model of acquired epilepsy.
8/2015The AMPA receptor antagonist NBQX exerts anti-seizure but not antiepileptogenic effects in the intrahippocampal kainate mouse model of mesial temporal lobe epilepsy.

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Friederike Twele Research Topics

Disease

12Seizures (Absence Seizure)
01/2021 - 11/2013
11Epilepsy (Aura)
01/2021 - 11/2013
7Temporal Lobe Epilepsy
01/2021 - 08/2015
6Status Epilepticus (Complex Partial Status Epilepticus)
01/2020 - 08/2015
2Partial Epilepsies (Epilepsy, Partial)
01/2020 - 08/2015
1Infections
01/2022
1Noncommunicable Diseases
08/2021
1COVID-19
07/2021
1Respiratory Tract Infections (Respiratory Tract Infection)
07/2020
1Brain Injuries (Brain Injury)
01/2020
1Ototoxicity
01/2016
1Brain Diseases (Brain Disorder)
02/2014

Drug/Important Bio-Agent (IBA)

10Kainic Acid (Kainate)IBA
01/2021 - 08/2015
6Pharmaceutical PreparationsIBA
01/2021 - 01/2016
3Drug CombinationsIBA
01/2021 - 01/2019
3Anticonvulsants (Antiepileptic Drugs)IBA
04/2016 - 02/2014
2Volatile Organic CompoundsIBA
01/2022 - 07/2020
2Levetiracetam (Keppra)FDA LinkGeneric
01/2021 - 01/2020
2Phenobarbital (Luminal)FDA Link
01/2020 - 01/2016
22,3- dioxo- 6- nitro- 7- sulfamoylbenzo(f)quinoxaline (NBQX)IBA
01/2017 - 08/2015
2AMPA Receptors (AMPA Receptor)IBA
01/2017 - 08/2015
2Sodium-Potassium-Chloride SymportersIBA
01/2016 - 02/2014
2Bumetanide (Bumex)FDA LinkGeneric
01/2016 - 02/2014
1Explosive Agents (Explosives)IBA
08/2021
1PropiolactoneFDA Link
07/2021
1Ceftriaxone (Ceftriaxon)FDA LinkGeneric
01/2021
1Atorvastatin (Lipitor)FDA Link
01/2021
1PQR530IBA
01/2020
1pqr620IBA
01/2020
1Adenosine Triphosphate (ATP)IBA
01/2020
1Topiramate (Topamax)FDA LinkGeneric
01/2020
1Proteins (Proteins, Gene)FDA Link
01/2020
1Mechanistic Target of Rapamycin Complex 1IBA
01/2020
1citrate-binding transport proteinIBA
01/2020
1Citric Acid (Citrate)FDA LinkGeneric
01/2020
1Sirolimus (Rapamycin)FDA Link
01/2020
1Neuroprotective AgentsIBA
01/2019
1Excitatory Amino Acid AntagonistsIBA
01/2017
1N-Methylaspartate (NMDA)IBA
01/2017
1salicylhydroxamic acid (SHAM)IBA
01/2017
1ifenprodilIBA
01/2017
1Pilocarpine (Ocusert)FDA LinkGeneric
04/2016
1Pentylenetetrazole (Metrazol)IBA
04/2016
1IsofluraneFDA LinkGeneric
02/2016
1Chloral HydrateIBA
02/2016
1Sodium Potassium Chloride Symporter Inhibitors (Loop Diuretics)IBA
01/2016
1Protein Isoforms (Isoforms)IBA
01/2016
1ChloridesIBA
01/2016
1Excitatory Amino Acid AgonistsIBA
01/2016
1Carbamazepine (Tegretol)FDA LinkGeneric
01/2016
1alpha- Amino- 3- hydroxy- 5- methyl- 4- isoxazolepropionic Acid (AMPA)IBA
08/2015
1Glutamate Receptors (Glutamate Receptor)IBA
08/2015
1Phenytoin (Dilantin)FDA LinkGeneric
08/2015
1perampanelIBA
08/2015
1DiureticsIBA
02/2014
1AWD 131-138IBA
11/2013

Therapy/Procedure

4Therapeutics
01/2020 - 08/2015
1Operative Surgical Procedures
01/2017
1Anesthesia
02/2016